Proscaline Microdose (Mescaline Analogue)
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Description
Proscaline Microdose (Mescaline Analogue)
Proscaline Microdose (Mescaline Analogue): Enhance Your Mental Clarity
Unlock a heightened state of awareness with Proscaline Microdose, a mescaline analogue known for its ability to enhance mental clarity and focus. This product is ideal for those looking to explore the cognitive benefits of microdosing. By incorporating Proscaline into your routine, you may experience improved creativity, sharper concentration, and a more balanced mood.
Key Benefits:
- Enhances mental clarity and focus
- Supports cognitive function and creativity
- Microdose formulation for easy use
- Mescaline analogue for a balanced mood
Usage and Dosage: To achieve the best results, start with a low dose and gradually adjust based on your needs. Always consult with a healthcare professional before beginning any new supplement regimen.
Proscaline Microdose – Overview & Considerations
Proscaline is a psychedelic compound in the phenethylamine class, structurally related to mescaline, but also similar to compounds like 3,4,5-trimethoxyamphetamine (TMA) and mescaline analogues such as 3C-P. It’s part of the 3,5-dimethoxy-4-substituted phenethylamine family, with the full chemical name: 3,5-dimethoxy-4-propoxyphenethylamine.
⚠️ LEGAL & SAFETY DISCLAIMER
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Legality: Proscaline is unscheduled in many countries but may fall under analogue laws (e.g., U.S. Federal Analog Act).
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Safety: There’s very little human data, so caution is critical. It is a research chemical with unknown long-term effects.
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Always test purity with reagent kits, use scales accurate to 0.001g (1 mg), and begin with ultra-low doses.
🔬 Microdosing Proscaline
Microdosing generally means taking about 1/10th to 1/20th of a threshold dose to obtain subtle cognitive/emotional benefits without full psychedelic effects.
1. Threshold Dose (Full Psychedelic)
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Approximate threshold dose: 20–30 mg
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Common active dose range: 30–60 mg
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Duration: 10–14 hours (can vary)
2. Microdose Range
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Microdose estimate: 1–5 mg
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Typical frequency (based on anecdotal reports): every 3rd day (similar to James Fadiman protocol)
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Duration of effects (microdoses): ~6–10 hours subtle uplift, depending on metabolism
⚙️ Expected Effects at Microdose Levels (Anecdotal)
Positive (Potential):
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Slight mood enhancement
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Increased energy or alertness
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Subtle sensory sharpening
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Enhanced creativity or introspection
Negative (Possible):
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Insomnia (due to long half-life)
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Mild anxiety or irritability
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GI discomfort
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Long tail of stimulation (can disrupt sleep)
🧠 Pharmacology
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Mechanism: Likely a 5-HT2A receptor agonist, similar to mescaline and other phenethylamines.
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Metabolism: Little is known, but likely metabolized hepatically; potential interactions with other serotonergic drugs.
📝 Important Tips
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Start very low: 1 mg is a good starting microdose for new users.
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Use a milligram scale and consider dilution in solution (e.g., in ethanol or distilled water) for precise microdosing.
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Avoid combining with MAOIs or SSRIs due to potential interactions.
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Keep a journal to track dose, mood, cognition, and any physiological effects.
🔍 Comparison to Other Microdosed Psychedelics
Compound | Typical Microdose | Duration | Subjective Profile |
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LSD | 5–15 µg | 8–12 hrs | Energetic, cognitive, uplifting |
Psilocybin | 0.1–0.3 g (mush) | 4–6 hrs | Emotional, intuitive, gentle |
Mescaline | 10–25 mg | 10–14 hrs | Heart-centered, warm, stimulating |
Proscaline | 1–5 mg | 10–14 hrs | Stimulating, mescaline-like, longer tail |
📚 References & Further Reading
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PiHKAL #121 (Shulgin’s entry on Proscaline)
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Erowid experiences (if available – sparse)
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Alexander Shulgin’s notes (empirical, not clinical)
Additional information
Quantity | 7g, 20g, 14g, 28g, 50g, 100g, 250g |
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